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Issue 9, 2016
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Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC

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Abstract

Cyclic olefin copolymer (COC) is widely used in microfluidics due to its UV-transparency, its biocompatibility and high chemical resistance. Here we present a fast and cost-effective solvent bonding technique, which allows for the efficient bonding of protein-patterned COC structures. The bonding process is carried out at room temperature and takes less than three minutes. Enzyme activity is retained upon bonding and microstructure deformation does not occur.

Graphical abstract: Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC

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Publication details

The article was received on 07 Dec 2015, accepted on 21 Mar 2016 and first published on 23 Mar 2016


Article type: Communication
DOI: 10.1039/C5LC01498K
Citation: Lab Chip, 2016,16, 1561-1564
  • Open access: Creative Commons BY license
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    Tacky cyclic olefin copolymer: a biocompatible bonding technique for the fabrication of microfluidic channels in COC

    N. Keller, T. M. Nargang, M. Runck, F. Kotz, A. Striegel, K. Sachsenheimer, D. Klemm, K. Länge, M. Worgull, C. Richter, D. Helmer and B. E. Rapp, Lab Chip, 2016, 16, 1561
    DOI: 10.1039/C5LC01498K

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