Jump to main content
Jump to site search

Volume 191, 2016
Previous Article Next Article

A multi-coordinating polymer ligand optimized for the functionalization of metallic nanocrystals and nanorods

Author affiliations

Abstract

We report the design and use of a multi-coordinating polymer ligand that is ideally suited for functionalizing gold nanoparticles and nanorods, and promoting their steric stabilization in buffer media. The ligand is prepared via a one-step nucleophilic addition reaction between poly(isobutylene-alt-maleic anhydride) and amine-modified anchoring groups and hydrophilic moieties. Surface functionalization of gold nanoparticles and nanorods with this polymer yields nanocrystals that exhibit excellent long-term colloidal stability over a broad range of conditions, including pH changes and in growth media, as verified using dynamic light scattering measurements combined with agarose gel electrophoresis. This polymer coating can also prevent the formation of protein corona. These features bode well for use in biological applications where small size, reduced nonspecific interactions and colloidal stability are highly desired. Furthermore, this design can be easily expanded to functionalize a variety of other inorganic nanocrystals.

Back to tab navigation

Publication details

The article was received on 17 Mar 2016, accepted on 22 Mar 2016 and first published on 23 Mar 2016


Article type: Paper
DOI: 10.1039/C6FD00056H
Citation: Faraday Discuss., 2016,191, 481-494
  •   Request permissions

    A multi-coordinating polymer ligand optimized for the functionalization of metallic nanocrystals and nanorods

    W. Wang, X. Ji, H. Burns and H. Mattoussi, Faraday Discuss., 2016, 191, 481
    DOI: 10.1039/C6FD00056H

Search articles by author

Spotlight

Advertisements