Pd–Co3[Co(CN)6]2 hybrid nanoparticles: preparation, characterization, and challenge for the Suzuki–Miyaura coupling of aryl chlorides under mild conditions

Abstract

Because of their abundance and low cost, organo chlorides are the most desirable substrates from the industrial point of view in Suzuki–Miyaura cross-coupling reactions. However, catalytic application of Pd nanoparticles (NPs) for Suzuki coupling of aryl chlorides is still a challenge. Here, we design a novel catalyst by combining Pd NPs with Co₃[Co(CN)₆]₂ nanocrystals for Suzuki–Miyaura coupling of aryl chlorides. This nanocatalyst demonstrated good activity (yield 86.2% at 80 °C), high TOF, great stability, easy separation, excellent reusability (initial rates were not reduced after five cycles) and low cost in Suzuki reactions.