Jump to main content
Jump to site search

Issue 8, 2016
Previous Article Next Article

Raman and DFT study of methimazole chemisorbed on gold colloidal nanoparticles

Author affiliations

Abstract

The adsorption of methimazole on gold colloidal nanoparticles was investigated using a combination of surface-enhanced Raman scattering and density functional theory calculations, which allowed identifying the thiolate anion as the molecular species chemically interacting with the active sites of the gold surface, modeled as zero-charge metal adatoms, only through the sulfur atom. This result can be important for the use of these ligand/metal nanohybrids in the process of drug delivery. Moreover, functionalized gold nanoparticles are able to promote the Raman enhancement in the red-light region as well as in the near-infrared, where generally no fluorescence emission occurs. This paves the way for the use of these nanosystems in a biological environment, even in vivo experiments.

Graphical abstract: Raman and DFT study of methimazole chemisorbed on gold colloidal nanoparticles

Back to tab navigation

Supplementary files

Publication details

The article was received on 09 Dec 2015, accepted on 25 Jan 2016 and first published on 25 Jan 2016


Article type: Paper
DOI: 10.1039/C5CP07597A
Author version
available:
Download author version (PDF)
Citation: Phys. Chem. Chem. Phys., 2016,18, 5974-5980
  •   Request permissions

    Raman and DFT study of methimazole chemisorbed on gold colloidal nanoparticles

    M. Muniz-Miranda, F. Muniz-Miranda and A. Pedone, Phys. Chem. Chem. Phys., 2016, 18, 5974
    DOI: 10.1039/C5CP07597A

Search articles by author

Spotlight

Advertisements