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Issue 55, 2016
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Secondary electrospray ionization coupled to high-resolution mass spectrometry reveals tryptophan pathway metabolites in exhaled human breath

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Abstract

Many studies and personalized medicine in general require frequent measurements and/or rapid results of biomarker levels. Here we show that 20 low volatility metabolites of the tryptophan pathway can be detected in exhaled human breath. This real-time and non-invasive method offers an attractive alternative to blood analysis.

Graphical abstract: Secondary electrospray ionization coupled to high-resolution mass spectrometry reveals tryptophan pathway metabolites in exhaled human breath

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Publication details

The article was received on 12 Apr 2016, accepted on 02 Jun 2016 and first published on 02 Jun 2016


Article type: Communication
DOI: 10.1039/C6CC03070J
Citation: Chem. Commun., 2016,52, 8526-8528
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    Secondary electrospray ionization coupled to high-resolution mass spectrometry reveals tryptophan pathway metabolites in exhaled human breath

    D. García-Gómez, T. Gaisl, L. Bregy, P. Martínez-Lozano Sinues, M. Kohler and R. Zenobi, Chem. Commun., 2016, 52, 8526
    DOI: 10.1039/C6CC03070J

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