Jump to main content
Jump to site search

Issue 46, 2016
Previous Article Next Article

Isomorphous template induced crystallisation: a robust method for the targeted crystallisation of computationally predicted metastable polymorphs

Author affiliations

Abstract

A new method of inducing the crystallisation of metastable polymorphs by isomorphous templating has been developed and used to reproduce the crystallisation of CBZ-V on the surface of DHC-II. Studies of the growth of CBZ-V on DHC-II single crystals show crystals growing laterally and vertically on DHC-II surfaces without any significant face selectivity. The generality of this computationally inspired crystallisation approach is demonstrated by producing the first crystals of an entirely new polymorph of cyheptamide, which is isomorphous to both DHC-II and CBZ-V.

Graphical abstract: Isomorphous template induced crystallisation: a robust method for the targeted crystallisation of computationally predicted metastable polymorphs

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 Feb 2016, accepted on 05 May 2016 and first published on 05 May 2016


Article type: Communication
DOI: 10.1039/C6CC01710J
Citation: Chem. Commun., 2016,52, 7384-7386
  •   Request permissions

    Isomorphous template induced crystallisation: a robust method for the targeted crystallisation of computationally predicted metastable polymorphs

    V. K. Srirambhatla, R. Guo, S. L. Price and A. J. Florence, Chem. Commun., 2016, 52, 7384
    DOI: 10.1039/C6CC01710J

Search articles by author

Spotlight

Advertisements