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Issue 21, 2016
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A peptide hydrogel derived from a fragment of human cardiac troponin C

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Abstract

The human cardiac troponin C peptide fragment H-V9EQLTEEQKNEFKAAFDIFVLGA31-OH, which covers helix-A in the native protein, self-assembles into β-sheet fibrils in solution. These fibrils further entangle to give a hydrogel. This peptide may therefore serve as a template for development of novel biomaterials.

Graphical abstract: A peptide hydrogel derived from a fragment of human cardiac troponin C

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Publication details

The article was received on 09 Jan 2016, accepted on 12 Feb 2016 and first published on 12 Feb 2016


Article type: Communication
DOI: 10.1039/C6CC00209A
Citation: Chem. Commun., 2016,52, 4056-4059
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    A peptide hydrogel derived from a fragment of human cardiac troponin C

    L. M. De Leon-Rodriguez, M. Kamalov, Y. Hemar, A. K. Mitra, V. Castelletto, D. Hermida-Merino, I. W. Hamley and M. A. Brimble, Chem. Commun., 2016, 52, 4056
    DOI: 10.1039/C6CC00209A

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