Issue 27, 2016
From the journal:

Chemical Communications

Ultrasensitive detection of microbial cells using magnetic focus enhanced lateral flow sensors†

Wen Ren,a   Il-Hoon Cho,b   Zhongwu Zhoua  and  Joseph Irudayaraj*a  

* Corresponding authors

a Department of Agricultural and Biological Engineering, Bindley Bioscience Center, Purdue Center for Cancer research, Purdue University, West Lafayette, Indiana 47907, USA
E-mail: josephi@purdue.edu

b Department of Biomedical Laboratory Science, College of Health Science, Eulji University, Seongnam 461-713, Republic of Korea

Abstract

We report on an improved lateral flow immunoassay (LFIA) sensor with a magnetic focus for ultrasensitive naked-eye detection of pathogenic microorganisms at a near single cell limit without any pre-enrichment steps, by allowing the magnetic probes to focus the labelled pathogens to the target zone of the LF strip.

Graphical abstract: Ultrasensitive detection of microbial cells using magnetic focus enhanced lateral flow sensors

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Article information

DOI
https://doi.org/10.1039/C5CC10240E
Article type
Communication
Submitted
13 Dec 2015
Accepted
26 Feb 2016
First published
26 Feb 2016

Chem. Commun., 2016,52, 4930-4933

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Ultrasensitive detection of microbial cells using magnetic focus enhanced lateral flow sensors

W. Ren, I. Cho, Z. Zhou and J. Irudayaraj, Chem. Commun., 2016, 52, 4930 DOI: 10.1039/C5CC10240E

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