Issue 15, 2016
From the journal:

Chemical Communications

Photoresponsive self-healing supramolecular hydrogels for light-induced release of DNA and doxorubicin†

Zbigniew L. Pianowski, ORCID logo *ab   Johannes Karchera  and  Knut Schneidera  

* Corresponding authors

a Institut für Organische Chemie, Karlsruher Institut für Technologie, Fritz-Haber-Weg 6, D-76131 Karlsruhe, Germany

b Institut für Toxikologie und Genetik, Karlsruher Institut für Technologie, Herman-von-Helmholtz Platz 1, D-76344 Eggenstein-Leopoldshafen, Germany
E-mail: pianowski@kit.edu

Abstract

An azobenzene-containing cyclic dipeptide PAP-DKP-Lys is a photoresponsive low-MW hydrogelator. The gelation process can be triggered with temperature, pH, light, and ionic strength. The resulting self-healing gels can encapsulate dsDNA or an anticancer drug doxorubicin, and release them in a light-dependent manner.

Graphical abstract: Photoresponsive self-healing supramolecular hydrogels for light-induced release of DNA and doxorubicin

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Article information

DOI
https://doi.org/10.1039/C5CC09633B
Article type
Communication
Submitted
20 Nov 2015
Accepted
19 Jan 2016
First published
19 Jan 2016

Chem. Commun., 2016,52, 3143-3146

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Photoresponsive self-healing supramolecular hydrogels for light-induced release of DNA and doxorubicin

Z. L. Pianowski, J. Karcher and K. Schneider, Chem. Commun., 2016, 52, 3143 DOI: 10.1039/C5CC09633B

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