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Issue 19, 2016
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Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

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Abstract

Fluorescent, aqueous-soluble, crosslinked dendronized polyols (CDPs) are obtained through a sequential process involving ring-opening metathesis polymerization (ROMP), intra-chain ring-closing metathesis (RCM), and hydrolysis. This general strategy improves the quantum yields (QYs), brightness, and photostability of five common fluorophores whose emission wavelengths cover 150 nm. Additionally, the availability of the polymeric fluorophore to the cytosomes opens the door to applications in bioimaging and intracellular delivery.

Graphical abstract: Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

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Publication details

The article was received on 13 Nov 2015, accepted on 01 Feb 2016 and first published on 01 Feb 2016


Article type: Communication
DOI: 10.1039/C5CC09430E
Citation: Chem. Commun., 2016,52, 3781-3784
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    Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores

    Y. Li, Y. Bai, N. Zheng, Y. Liu, G. A. Vincil, B. J. Pedretti, J. Cheng and S. C. Zimmerman, Chem. Commun., 2016, 52, 3781
    DOI: 10.1039/C5CC09430E

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