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Issue 11, 2016
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A naphthalimide derived fluorescent sensor for solid-phase screening of cucurbit[7]uril–guest interactions

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Abstract

A naphthalimide based fluorescent sensor displaying a significant increase in emission upon binding CB[7] with notable pH stability was developed and utilized in a surface-bound displacement assay for the rapid detection of CB[7] encapsulation of therapeutically relevant drug classes. Previously unknown binders with moderate to strong affinities were discovered.

Graphical abstract: A naphthalimide derived fluorescent sensor for solid-phase screening of cucurbit[7]uril–guest interactions

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Publication details

The article was received on 07 Oct 2015, accepted on 16 Dec 2015 and first published on 16 Dec 2015


Article type: Communication
DOI: 10.1039/C5CC08350H
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Citation: Chem. Commun., 2016,52, 2307-2310
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    A naphthalimide derived fluorescent sensor for solid-phase screening of cucurbit[7]uril–guest interactions

    G. H. Aryal, C. H. Battle, T. A. Grusenmeyer, M. Zhu and J. Jayawickramarajah, Chem. Commun., 2016, 52, 2307
    DOI: 10.1039/C5CC08350H

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