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Issue 20, 2016
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A plasmonic chip-based bio/chemical hybrid sensing system for the highly sensitive detection of C-reactive protein

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Abstract

A synthetic polymer ligand-grafted plasmonic chip was fabricated and demonstrated a highly sensitive detection of C-reactive protein (CRP) by grating-coupled surface plasmon field-enhanced fluorescence. Poly(2-methacryloyloxyethyl-phosphorylcholine) was used as a CRP-specific polymer ligand layer and was grafted onto the plasmonic chip using surface-initiated controlled/living radical polymerization (limit of detection: ca. 10 pM).

Graphical abstract: A plasmonic chip-based bio/chemical hybrid sensing system for the highly sensitive detection of C-reactive protein

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Publication details

The article was received on 19 Sep 2015, accepted on 26 Nov 2015 and first published on 10 Dec 2015


Article type: Communication
DOI: 10.1039/C5CC07868G
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2016,52, 3883-3886
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    A plasmonic chip-based bio/chemical hybrid sensing system for the highly sensitive detection of C-reactive protein

    R. Matsuura, K. Tawa, Y. Kitayama and T. Takeuchi, Chem. Commun., 2016, 52, 3883
    DOI: 10.1039/C5CC07868G

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