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Issue 3, 2016
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Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation

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Abstract

Recent studies have demonstrated that metal–organic frameworks can be employed as protective coatings for enzymes. Two efficient strategies have been reported for the synthesis of such composite materials: biomimetic mineralisation and controlled co-precipitation using polyvinylpyrrolidone. We assessed the relative efficacy of each approach by comparing the thermal stability of encapsulated urease. The resulting data shows that over a range of temperatures biomimetic mineralisation offers superior protection than the co-precipitation method.

Graphical abstract: Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation

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Publication details

The article was received on 10 Sep 2015, accepted on 30 Oct 2015 and first published on 02 Nov 2015


Article type: Communication
DOI: 10.1039/C5CC07577G
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2016,52, 473-476
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    Enzyme encapsulation in zeolitic imidazolate frameworks: a comparison between controlled co-precipitation and biomimetic mineralisation

    K. Liang, C. J. Coghlan, S. G. Bell, C. Doonan and P. Falcaro, Chem. Commun., 2016, 52, 473
    DOI: 10.1039/C5CC07577G

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