Issue 1, 2016
From the journal:

Chemical Communications

A two-photon fluorescent probe for lysosomal zinc ions†

Hyo-Jun Lee,‡a   Chang-Woo Cho,*a   Hyewon Seo,‡b   Subhankar Singha,‡b   Yong Woong Jun,b   Kyung-Ha Lee,c   Youngseob Jung,c   Kyong-Tai Kim,c   Seongjun Park,d   Sung Chul Baed  and  Kyo Han Ahn*b  

* Corresponding authors

a Department of Chemistry, Kyungpook National University, Daegu 702-701, Republic of Korea
E-mail: cwcho@knu.ac.kr

b Department of Chemistry, POSTECH, Pohang 790-784, Republic of Korea
E-mail: ahn@postech.ac.kr

c Division of Integrative Biosciences and Biotechnology, POSTECH, Pohang 790-784, Republic of Korea

d School of Life Sciences, UNIST, Ulsan 689-798, Republic of Korea

Abstract

The selective detection of zinc ions in lysosomes over that in cytosol is achieved with a fluorescent probe, which enabled the fluorescence imaging of endogenous zinc ions in lysosomes of NIH 3T3 cells as well as mouse hippocampal tissues by two-photon microscopy under excitation at 900 nm.

Graphical abstract: A two-photon fluorescent probe for lysosomal zinc ions

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Article information

DOI
https://doi.org/10.1039/C5CC06976A
Article type
Communication
Submitted
19 Aug 2015
Accepted
19 Oct 2015
First published
21 Oct 2015

Chem. Commun., 2016,52, 124-127

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A two-photon fluorescent probe for lysosomal zinc ions

H. Lee, C. Cho, H. Seo, S. Singha, Y. W. Jun, K. Lee, Y. Jung, K. Kim, S. Park, S. C. Bae and K. H. Ahn, Chem. Commun., 2016, 52, 124 DOI: 10.1039/C5CC06976A

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