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Issue 13, 2016
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Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

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Abstract

The signal enhancement properties of QCM sensors based on dynamic, biotinylated poly(acrylic acid) brushes has been studied in interaction studies with an anti-biotin Fab fragment. The poly(acrylic acid) sensors showed a dramatic increase in signal response with more than ten times higher signal than the carboxyl-terminated self-assembled monolayer surface.

Graphical abstract: Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

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Publication details

The article was received on 29 Mar 2016, accepted on 11 May 2016 and first published on 12 May 2016


Article type: Communication
DOI: 10.1039/C6AN00735J
Citation: Analyst, 2016,141, 3993-3996
  • Open access: Creative Commons BY-NC license
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    Signal enhancement in ligand–receptor interactions using dynamic polymers at quartz crystal microbalance sensors

    G. Dunér, H. Anderson, Z. Pei, B. Ingemarsson, T. Aastrup and O. Ramström, Analyst, 2016, 141, 3993
    DOI: 10.1039/C6AN00735J

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