Jump to main content
Jump to site search

Issue 38, 2015
Previous Article Next Article

Soft microcapsules with highly plastic shells formed by interfacial polyelectrolyte–nanoparticle complexation

Author affiliations

Abstract

Composite microcapsules have been aggressively pursued as designed chemical entities for biomedical and other applications. Common preparations rely on multi-step, time consuming processes. Here, we present a single-step approach to fabricate such microcapsules with shells composed of nanoparticle–polyelectrolyte and protein–polyelectrolyte complexes, and demonstrate control of the mechanical and release properties of these constructs. Interfacial polyelectrolyte–nanoparticle and polyelectrolyte–protein complexation across a water–oil droplet interface results in the formation of capsules with shell thicknesses of a few μm. Silica shell microcapsules exhibited a significant plastic response at small deformations, whereas lysozyme incorporated shells displayed a more elastic response. We exploit the plasticity of nanoparticle incorporated shells to produce microcapsules with high aspect ratio protrusions by micropipette aspiration.

Graphical abstract: Soft microcapsules with highly plastic shells formed by interfacial polyelectrolyte–nanoparticle complexation

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Apr 2015, accepted on 07 Jul 2015 and first published on 07 Jul 2015


Article type: Paper
DOI: 10.1039/C5SM00973A
Author version available: Download Author version (PDF)
Citation: Soft Matter, 2015,11, 7478-7482
  •   Request permissions

    Soft microcapsules with highly plastic shells formed by interfacial polyelectrolyte–nanoparticle complexation

    G. Kaufman, S. Nejati, R. Sarfati, R. Boltyanskiy, M. Loewenberg, E. R. Dufresne and C. O. Osuji, Soft Matter, 2015, 11, 7478
    DOI: 10.1039/C5SM00973A

Search articles by author

Spotlight

Advertisements