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Issue 22, 2015
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Comprehensive chemical secretory measurement of single cells trapped in a micro-droplet array with mass spectrometry

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Abstract

Secretomics, the comprehensive study of cell releasates, offers a non-invasive approach to understanding cell heterogeneity. We here propose single cell small molecule secretomics using micro-droplet arrays and mass spectrometry as a new repertoire of omics technologies. The present method revealed the heterogeneity of secreted small molecules from individual single cells without the use of any invasive processes.

Graphical abstract: Comprehensive chemical secretory measurement of single cells trapped in a micro-droplet array with mass spectrometry

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Publication details

The article was received on 09 Oct 2014, accepted on 29 Jan 2015 and first published on 30 Jan 2015


Article type: Communication
DOI: 10.1039/C4RA12021C
Author version available: Download Author version (PDF)
Citation: RSC Adv., 2015,5, 16968-16971
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    Comprehensive chemical secretory measurement of single cells trapped in a micro-droplet array with mass spectrometry

    H. Fujita, T. Esaki, T. Masujima, A. Hotta, S. H. Kim, H. Noji and T. M. Watanabe, RSC Adv., 2015, 5, 16968
    DOI: 10.1039/C4RA12021C

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