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Issue 128, 2015
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A supramolecular hydrogel for generation of a benign DNA-hydrogel

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Abstract

A novel hydrogel has been synthesized using 2′,4′,6′-tri(4-pyridyl)pyridine in an acidic water medium. TEM analyses along with rheological experiments explore the supramolecular features of the hydrogel. In vitro and in vivo toxicity studies depict the non-toxic and bio-relevant nature of the pure supramolecular hydrogel and its aqueous solution. This bio-compatible supramolecular hydrogel is used for the synthesis of a DNA-hydrogel with calf thymus DNA. The DNA-hydrogel is intriguing for the effective stabilization of photochemically synthesized silver nanoparticles from Ag(I) under the direct exposure of sunrays. DNA-hydrogel capped Ag-NPs are also bio-compatible. The luminous features of the 2′,4′,6′-tri(4-pyridyl)pyridine based supramolecular hydrogel, DNA-hydrogel and DNA-hydrogel capped Ag-NPs and their aqueous solutions are explored through fluorescence microscopy and spectral analyses, respectively.

Graphical abstract: A supramolecular hydrogel for generation of a benign DNA-hydrogel

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Publication details

The article was received on 17 Sep 2015, accepted on 25 Nov 2015 and first published on 26 Nov 2015


Article type: Paper
DOI: 10.1039/C5RA19172F
Citation: RSC Adv., 2015,5, 105961-105968
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    A supramolecular hydrogel for generation of a benign DNA-hydrogel

    B. Dey, R. K. Mondal, S. Mukherjee, B. Satpati, N. Mukherjee, A. Mandal, D. Senapati and S. P. Sinha Babu, RSC Adv., 2015, 5, 105961
    DOI: 10.1039/C5RA19172F

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