Jump to main content
Jump to site search

Issue 61, 2015
Previous Article Next Article

Two-photon absorption of polyfluorene aggregates stabilized by insulin amyloid fibrils

Author affiliations

Abstract

We report on the photophysical and optical properties of a polyfluorene derivative (PFO) and its binding to the amyloid-forming protein insulin. The complexation is based on weak supramolecular interactions between amyloid fibrils and PFO in dissolved and aggregated forms. In particular, complexes of polyfluorene aggregates display sizeable two-photon absorption when stabilized by insulin fibril nanotemplates. We propose that a two-photon absorption enhancement mechanism is related to the combination of through-bond and through-space interactions of PFO. The findings reported here suggest that polyfluorene aggregates offer good nonlinear absorption properties and can be used as molecular markers for amyloid fibril recognition.

Graphical abstract: Two-photon absorption of polyfluorene aggregates stabilized by insulin amyloid fibrils

Back to tab navigation

Supplementary files

Publication details

The article was received on 05 May 2015, accepted on 22 May 2015 and first published on 26 May 2015


Article type: Paper
DOI: 10.1039/C5RA08302H
Citation: RSC Adv., 2015,5, 49363-49368
  • Open access: Creative Commons BY license
  •   Request permissions

    Two-photon absorption of polyfluorene aggregates stabilized by insulin amyloid fibrils

    P. Hanczyc, A. Justyniarski, D. A. Gedefaw, M. R. Andersson, M. Samoc and C. Müller, RSC Adv., 2015, 5, 49363
    DOI: 10.1039/C5RA08302H

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements