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Issue 62, 2015
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KOtBu mediated efficient approach for the synthesis of fused heterocycles via intramolecular O-/N-arylations

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Abstract

A novel and efficient methodology for the synthesis of 6H-benzo[c]chromenes, 6H-benzo[c]chromen-6-ones, carbazoles, dibenzofurans, dibenzooxepins has been developed. The reaction goes through intramolecular O-/N-arylations with sp2C–Br bonds via typical SNAr pathway in presence of potassium-tert-butoxide base.

Graphical abstract: KOtBu mediated efficient approach for the synthesis of fused heterocycles via intramolecular O-/N-arylations

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The article was received on 25 Apr 2015, accepted on 01 Jun 2015 and first published on 01 Jun 2015


Article type: Communication
DOI: 10.1039/C5RA07532G
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Citation: RSC Adv., 2015,5, 50174-50177
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    KOtBu mediated efficient approach for the synthesis of fused heterocycles via intramolecular O-/N-arylations

    R. Singha, A. Ahmed, Y. Nuree, M. Ghosh and J. K. Ray, RSC Adv., 2015, 5, 50174
    DOI: 10.1039/C5RA07532G

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