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Issue 51, 2015
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Enantioselective total synthesis of (+)-serinolamide A

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Abstract

A short and highly efficient enantioselective synthetic approach to (+)-serinolamide A 1 from racemic butadiene monoepoxide as a starting material is described. The synthesis utilizes the palladium catalyzed Trost's Dynamic Kinetic Asymmetric Transformation (DYKAT) and cross-metathesis (CM) as key steps.

Graphical abstract: Enantioselective total synthesis of (+)-serinolamide A

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Publication details

The article was received on 13 Apr 2015, accepted on 29 Apr 2015 and first published on 29 Apr 2015


Article type: Paper
DOI: 10.1039/C5RA06609C
Author version available: Download Author version (PDF)
Citation: RSC Adv., 2015,5, 41013-41016
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    Enantioselective total synthesis of (+)-serinolamide A

    S. Gahalawat and S. K. Pandey, RSC Adv., 2015, 5, 41013
    DOI: 10.1039/C5RA06609C

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