Issue 51, 2015
From the journal:

RSC Advances

Enantioselective total synthesis of (+)-serinolamide A†‡

Suraksha Gahalawata  and  Satyendra Kumar Pandey*a  

* Corresponding authors

a School of Chemistry and Biochemistry, Thapar University, Patiala 147001, India
E-mail: skpandey@thapar.edu
Fax: +91-175-236-4498
Tel: +91-175-239-3832

Abstract

A short and highly efficient enantioselective synthetic approach to (+)-serinolamide A 1 from racemic butadiene monoepoxide as a starting material is described. The synthesis utilizes the palladium catalyzed Trost's Dynamic Kinetic Asymmetric Transformation (DYKAT) and cross-metathesis (CM) as key steps.

Graphical abstract: Enantioselective total synthesis of (+)-serinolamide A

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Article information

DOI
https://doi.org/10.1039/C5RA06609C
Article type
Paper
Submitted
13 Apr 2015
Accepted
29 Apr 2015
First published
29 Apr 2015

RSC Adv., 2015,5, 41013-41016

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Enantioselective total synthesis of (+)-serinolamide A

S. Gahalawat and S. K. Pandey, RSC Adv., 2015, 5, 41013 DOI: 10.1039/C5RA06609C

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