Jump to main content
Jump to site search

Issue 80, 2015
Previous Article Next Article

Synthesis, characterization, thermal behavior, and biological activity of ozonides from vegetable oils

Author affiliations

Abstract

In this work, we have synthesized ozonides from sunflower, flaxseed and baru oils. In addition, ozonolysis reaction of sunflower oil in the presence of water was performed, and the product obtained had high viscosity and a gel-like appearance. The ozonated products were investigated for their antimicrobial activity and cytotoxicity. The oleogel, with an MIC ≤ 3 mg mL−1, exhibited excellent antimicrobial activity against standard and clinical strains. All products showed no cytotoxicity when tested against NIH/3T3 murine fibroblast cells. Effects of ozonation time on the oils were analyzed by IR, 1H and 13C NMR spectroscopy. DSC analysis shows that the ozonides of vegetable oils decompose with a peak at about 150 °C and with a broad exotherm. The decomposition enthalpy is proportional to the degree of ozonation reached.

Graphical abstract: Synthesis, characterization, thermal behavior, and biological activity of ozonides from vegetable oils

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Feb 2015, accepted on 27 Jul 2015 and first published on 27 Jul 2015


Article type: Paper
DOI: 10.1039/C5RA02798E
Author version available: Download Author version (PDF)
Citation: RSC Adv., 2015,5, 65427-65436
  •   Request permissions

    Synthesis, characterization, thermal behavior, and biological activity of ozonides from vegetable oils

    N. Rodrigues de Almeida Kogawa, E. José de Arruda, A. C. Micheletti, M. de Fatima Cepa Matos, L. C. Silva de Oliveira, D. Pires de Lima, N. C. Pereira Carvalho, P. Dias de Oliveira, M. de Castro Cunha, M. Ojeda and A. Beatriz, RSC Adv., 2015, 5, 65427
    DOI: 10.1039/C5RA02798E

Search articles by author

Spotlight

Advertisements