Issue 11, 2015
From the journal:

RSC Advances

A two step protocol for the synthesis of highly substituted benzobicyclo[2.2.2]octadienone derivatives from 2-methoxyphenols†

Santhosh Kumar Chittimalla,*a   Chennakesavulu Bandia  and  Sireesha Putturua  

* Corresponding authors

a Medicinal Chemistry Department, AMRI Singapore Research Centre, 61 Science Park Road, #05-01, The Galen, Science Park III, Singapore 117525, Singapore
E-mail: santhosh.chittimalla@amriglobal.com, chemcsk@gmail.com
Fax: +65-63985511

Abstract

A rapid process for the synthesis of functionally rich benzobicyclo[2.2.2]octadienone derivatives has been realized through oxidative dimerization of commercially/readily available 2-methoxyphenols followed by an aromatization sequence.

Graphical abstract: A two step protocol for the synthesis of highly substituted benzobicyclo[2.2.2]octadienone derivatives from 2-methoxyphenols

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Article information

DOI
https://doi.org/10.1039/C4RA14219E
Article type
Communication
Submitted
10 Nov 2014
Accepted
19 Dec 2014
First published
19 Dec 2014

RSC Adv., 2015,5, 8050-8055

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A two step protocol for the synthesis of highly substituted benzobicyclo[2.2.2]octadienone derivatives from 2-methoxyphenols

S. K. Chittimalla, C. Bandi and S. Putturu, RSC Adv., 2015, 5, 8050 DOI: 10.1039/C4RA14219E

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