*                        
                        
                            Corresponding authors
                                                                                                            
                    
                    
                        
                                a
                        
                        
                            Department of Biomedical Engineering, Yonsei University, Maeji 234, Heungup, Wonju, Gangwondo, Republic of Korea 220-710
                                                                                                            
                    
                    
                        
                                b
                        
                        
                            Department of Radiology, College of Medicine, Yonsei University, Shinchon, Seodaemoon, Seoul, Republic of Korea 120-752
                                
                                E-mail:
                                    177hum@yuhs.ac,                                     jss@yuhs.ac                                                                                                            
                    
                    
                        
                                c
                        
                        
                            Nanomedical National Core Research Center, Yonsei University, Shinchon, Seodaemoon, Seoul, Republic of Korea 120-749
                                                                                                            
                    
                    
                        
                                d
                        
                        
                            Department of Chemical and Biomolecular Engineering, Yonsei University, Shinchon, Seodaemoon, Seoul, Republic of Korea 120-749
                                                                                                            
                    
                    
                        
                                e
                        
                        
                            Brain Korea 21 Plus Project for Medical Science, Yonsei University, Shinchon, Seodaemoon, Seoul, Republic of Korea 120-752
                                                                                                            
                    
                    
                        
                                f
                        
                        
                            YUHS-KRIBB Medical Convergence Research Institute, Shinchon, Seodaemoon, Seoul, Republic of Korea 120-752
                                                                                                            
                    
                    
                        
                                g
                        
                        
                            School of Biomedical Engineering, Korea University, Anam 5, Seingbuk, Seoul, Republic of Korea 136-701