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Issue 45, 2015
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Chemical sporulation and germination: cytoprotective nanocoating of individual mammalian cells with a degradable tannic acid–FeIII complex

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Abstract

Individual mammalian cells were coated with cytoprotective and degradable films by cytocompatible processes maintaining the cell viability. Three types of mammalian cells (HeLa, NIH 3T3, and Jurkat cells) were coated with a metal–organic complex of tannic acid (TA) and ferric ion, and the TA–FeIII nanocoat effectively protected the coated mammalian cells against UV-C irradiation and a toxic compound. More importantly, the cell proliferation was controlled by programmed formation and degradation of the TA–FeIII nanocoat, mimicking the sporulation and germination processes found in nature.

Graphical abstract: Chemical sporulation and germination: cytoprotective nanocoating of individual mammalian cells with a degradable tannic acid–FeIII complex

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Publication details

The article was received on 17 Aug 2015, accepted on 20 Oct 2015 and first published on 22 Oct 2015


Article type: Communication
DOI: 10.1039/C5NR05573C
Author version available: Download Author version (PDF)
Citation: Nanoscale, 2015,7, 18918-18922
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    Chemical sporulation and germination: cytoprotective nanocoating of individual mammalian cells with a degradable tannic acid–FeIII complex

    J. Lee, H. Cho, J. Choi, D. Kim, D. Hong, J. H. Park, S. H. Yang and I. S. Choi, Nanoscale, 2015, 7, 18918
    DOI: 10.1039/C5NR05573C

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