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Issue 26, 2015
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Two-colour fluorescent imaging in organisms using self-assembled nano-systems of upconverting nanoparticles and molecular switches

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Abstract

The water-insolubility of a potentially versatile photoresponsive ‘turn-on’ fluorescence probe was overcome by incorporating it into a nano-assembly containing an upconverting nanoparticle wrapped in an amphiphilic polymer. The appeal of the nano-system is not only in the ability to turn “on” and “off” the fluorescence from the organic chromophore using UV and visible light, it is in the fact that the nanoparticle acts as a static probe because it emits red and green light when excited by near infrared light, which is not effected by UV and visible light. This dual-functioning emission behaviour was demonstrated in live organisms.

Graphical abstract: Two-colour fluorescent imaging in organisms using self-assembled nano-systems of upconverting nanoparticles and molecular switches

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Publication details

The article was received on 10 May 2015, accepted on 29 May 2015 and first published on 03 Jun 2015


Article type: Communication
DOI: 10.1039/C5NR03058G
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Citation: Nanoscale, 2015,7, 11263-11266
  • Open access: Creative Commons BY-NC license
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    Two-colour fluorescent imaging in organisms using self-assembled nano-systems of upconverting nanoparticles and molecular switches

    T. Wu, B. Johnsen, Z. Qin, M. Morimoto, D. Baillie, M. Irie and N. R. Branda, Nanoscale, 2015, 7, 11263
    DOI: 10.1039/C5NR03058G

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