Facile construction of 3-indolochromenes and 3-indoloxanthenes via EDDF catalyzed one-pot three component reactions

Anuj Thakur; P. Linga Reddy; Mohit Tripathi; Diwan S. Rawat

doi:10.1039/C5NJ01288K

Facile construction of 3-indolochromenes and 3-indoloxanthenes via EDDF catalyzed one-pot three component reactions

Anuj Thakur,^a P. Linga Reddy,^a Mohit Tripathi^a and Diwan S. Rawat*^a

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* Corresponding authors

^a Department of Chemistry, University of Delhi, Delhi-110007
E-mail: dsrawat@chemistry.du.ac.in
Fax: +91-11-27667501
Tel: +91-11-27662683

Abstract

A novel and green strategy for the construction of biologically relevant 3-indolochromene and 3-indoloxanthene scaffolds is reported using EDDF as a catalyst and ethylene glycol as a promoter solvent. The catalytic system offers wider applicability, crossing over a variety of substrates, besides affording exclusively the desired product in shorter reaction times and high yields. Furthermore, the ease of work-up and purification combined with the recyclability of the EDDF–ethylene glycol system makes the present method environmentally sustainable and amenable to large-scale synthesis as well.

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Publication details

The article was received on 21 May 2015, accepted on 08 Jun 2015 and first published on 09 Jun 2015

Article type: Paper

DOI: 10.1039/C5NJ01288K

Author version available: Download Author version (PDF)

Citation: New J. Chem., 2015,39, 6253-6260

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Facile construction of 3-indolochromenes and 3-indoloxanthenes via EDDF catalyzed one-pot three component reactions

A. Thakur, P. Linga Reddy, M. Tripathi and D. S. Rawat, New J. Chem., 2015, 39, 6253
DOI: 10.1039/C5NJ01288K
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New Journal of Chemistry

Facile construction of 3-indolochromenes and 3-indoloxanthenes via EDDF catalyzed one-pot three component reactions

Abstract

Supplementary files

Publication details

Facile construction of 3-indolochromenes and 3-indoloxanthenes via EDDF catalyzed one-pot three component reactions

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