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Issue 15, 2015
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Bioprinting of 3D hydrogels

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Abstract

Three-dimensional (3D) bioprinting has recently emerged as an extension of 3D material printing, by using biocompatible or cellular components to build structures in an additive, layer-by-layer methodology for encapsulation and culture of cells. These 3D systems allow for cell culture in a suspension for formation of highly organized tissue or controlled spatial orientation of cell environments. The in vitro 3D cellular environments simulate the complexity of an in vivo environment and natural extracellular matrices (ECM). This paper will focus on bioprinting utilizing hydrogels as 3D scaffolds. Hydrogels are advantageous for cell culture as they are highly permeable to cell culture media, nutrients, and waste products generated during metabolic cell processes. They have the ability to be fabricated in customized shapes with various material properties with dimensions at the micron scale. 3D hydrogels are a reliable method for biocompatible 3D printing and have applications in tissue engineering, drug screening, and organ on a chip models.

Graphical abstract: Bioprinting of 3D hydrogels

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Publication details

The article was first published on 11 Jun 2015


Article type: Focus
DOI: 10.1039/C5LC90069G
Citation: Lab Chip, 2015,15, 3111-3115
  • Open access: Creative Commons BY-NC license
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    Bioprinting of 3D hydrogels

    M. M. Stanton, J. Samitier and S. Sánchez, Lab Chip, 2015, 15, 3111
    DOI: 10.1039/C5LC90069G

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      [Original citation] - Published by The Royal Society of Chemistry.

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