Issue 22, 2015

Review: in vitro microvessel models

Abstract

A wide range of perfusable microvessel models have been developed, exploiting advances in microfabrication, microfluidics, biomaterials, stem cell technology, and tissue engineering. These models vary in complexity and physiological relevance, but provide a diverse tool kit for the study of vascular phenomena and methods to vascularize artificial organs. Here we review the state-of-the-art in perfusable microvessel models, summarizing the different fabrication methods and highlighting advantages and limitations.

Graphical abstract: Review: in vitro microvessel models

Article information

Article type
Critical Review
Submitted
16 Jul 2015
Accepted
02 Sep 2015
First published
02 Sep 2015

Lab Chip, 2015,15, 4242-4255

Author version available

Review: in vitro microvessel models

M. I. Bogorad, J. DeStefano, J. Karlsson, A. D. Wong, S. Gerecht and P. C. Searson, Lab Chip, 2015, 15, 4242 DOI: 10.1039/C5LC00832H

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