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Issue 22, 2015
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Review: in vitro microvessel models

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Abstract

A wide range of perfusable microvessel models have been developed, exploiting advances in microfabrication, microfluidics, biomaterials, stem cell technology, and tissue engineering. These models vary in complexity and physiological relevance, but provide a diverse tool kit for the study of vascular phenomena and methods to vascularize artificial organs. Here we review the state-of-the-art in perfusable microvessel models, summarizing the different fabrication methods and highlighting advantages and limitations.

Graphical abstract: Review: in vitro microvessel models

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Publication details

The article was received on 16 Jul 2015, accepted on 02 Sep 2015 and first published on 02 Sep 2015


Article type: Critical Review
DOI: 10.1039/C5LC00832H
Author version available: Download Author version (PDF)
Citation: Lab Chip, 2015,15, 4242-4255
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    Review: in vitro microvessel models

    M. I. Bogorad, J. DeStefano, J. Karlsson, A. D. Wong, S. Gerecht and P. C. Searson, Lab Chip, 2015, 15, 4242
    DOI: 10.1039/C5LC00832H

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