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Issue 6, 2015
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Integrating nanopore sensors within microfluidic channel arrays using controlled breakdown

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Abstract

Nanopore arrays are fabricated by controlled dielectric breakdown (CBD) in solid-state membranes integrated within polydimethylsiloxane (PDMS) microfluidic devices. This technique enables the scalable production of independently addressable nanopores. By confining the electric field within the microfluidic architecture, nanopore fabrication is precisely localized and electrical noise is significantly reduced. Both DNA and protein molecules are detected to validate the performance of this sensing platform.

Graphical abstract: Integrating nanopore sensors within microfluidic channel arrays using controlled breakdown

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Publication details

The article was received on 19 Nov 2014, accepted on 19 Jan 2015 and first published on 19 Jan 2015


Article type: Technical Innovation
DOI: 10.1039/C4LC01366B
Citation: Lab Chip, 2015,15, 1407-1411
  • Open access: Creative Commons BY-NC license
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    Integrating nanopore sensors within microfluidic channel arrays using controlled breakdown

    R. Tahvildari, E. Beamish, V. Tabard-Cossa and M. Godin, Lab Chip, 2015, 15, 1407
    DOI: 10.1039/C4LC01366B

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