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Issue 4, 2015
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Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting

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Abstract

Particle sorting using acoustofluidics has enormous potential but widespread adoption has been limited by complex device designs and low throughput. Here, we report high-throughput separation of particles and T lymphocytes (600 μL min−1) by altering the net sonic velocity to reposition acoustic pressure nodes in a simple two-channel device. The approach is generalizable to other microfluidic platforms for rapid, high-throughput analysis.

Graphical abstract: Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting

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Publication details

The article was received on 11 Nov 2014, accepted on 23 Dec 2014 and first published on 07 Jan 2015


Article type: Technical Innovation
DOI: 10.1039/C4LC01342E
Citation: Lab Chip, 2015,15, 1000-1003
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    Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting

    S. Jung, T. Notton, E. Fong, M. Shusteff and L. S. Weinberger, Lab Chip, 2015, 15, 1000
    DOI: 10.1039/C4LC01342E

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