Jump to main content
Jump to site search

Issue 8, 2015
Previous Article Next Article

Eco-friendly chemoselective N-functionalization of isatins mediated by supported KF in 2-MeTHF

Author affiliations

Abstract

A sustainable, efficient method for the chemoselective N-functionalization of isatins based on the use of KF-Celite in 2-methyltetrahydrofuran is reported. Notably, the protocol allows reactions with a wide range of electrophiles such as alkyl halides, isocyanates and Michael acceptors.

Graphical abstract: Eco-friendly chemoselective N-functionalization of isatins mediated by supported KF in 2-MeTHF

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 May 2015, accepted on 07 Jul 2015 and first published on 08 Jul 2015


Article type: Communication
DOI: 10.1039/C5GC01002K
Citation: Green Chem., 2015,17, 4194-4197
  •   Request permissions

    Eco-friendly chemoselective N-functionalization of isatins mediated by supported KF in 2-MeTHF

    A. D. Mamuye, S. Monticelli, L. Castoldi, W. Holzer and V. Pace, Green Chem., 2015, 17, 4194
    DOI: 10.1039/C5GC01002K

Search articles by author

Spotlight

Advertisements