Jump to main content
Jump to site search

Issue 14, 2015
Previous Article Next Article

Collision cross section measurements for biomolecules within a high-resolution FT-ICR cell: theory

Author affiliations

Abstract

In this study, an energetic hard-sphere ion–neutral collision model was proposed to bridge-link ion collision cross section (CCS) with the image current collected from a high-resolution Fourier transform ion cyclotron resonance (FT-ICR) cell. By investigating the nonlinear effects induced by high-order electric fields and image charge forces, the energetic hard-sphere collision model was validated through experiments. Suitable application regions for the energetic hard-sphere collision model, as well as for the conventional Langevin and hard-sphere collision models, were also discussed. The energetic hard-sphere collision model was applied in the extraction of ion CCSs from high-resolution FT-ICR mass spectra. Discussions in the present study also apply to FT-Orbitraps and FT-quadrupole ion traps.

Graphical abstract: Collision cross section measurements for biomolecules within a high-resolution FT-ICR cell: theory

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Dec 2014, accepted on 26 Feb 2015 and first published on 02 Mar 2015


Article type: Paper
DOI: 10.1039/C4CP06065B
Author version available: Download Author version (PDF)
Citation: Phys. Chem. Chem. Phys., 2015,17, 9060-9067
  •   Request permissions

    Collision cross section measurements for biomolecules within a high-resolution FT-ICR cell: theory

    D. Guo, Y. Xin, D. Li and W. Xu, Phys. Chem. Chem. Phys., 2015, 17, 9060
    DOI: 10.1039/C4CP06065B

Search articles by author

Spotlight

Advertisements