Issue 22, 2015

Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and LC-MS/MS

Abstract

We report here label-free metabolite–protein adduct detection and identification employing magnetic beads coated with metabolic enzymes as bioreactors to generate metabolites and possible metabolite–protein adducts for analysis by liquid chromatography-tandem mass spectrometry.

Graphical abstract: Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and LC-MS/MS

Supplementary files

Article information

Article type
Communication
Submitted
15 Jan 2015
Accepted
11 Feb 2015
First published
11 Feb 2015

Chem. Commun., 2015,51, 4701-4703

Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and LC-MS/MS

D. Li, Y. Fu and J. F. Rusling, Chem. Commun., 2015, 51, 4701 DOI: 10.1039/C5CC00420A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements