Issue 99, 2015
From the journal:

Chemical Communications

Raman/fluorescence dual-sensing and imaging of intracellular pH distribution†

Yue Cao,a   Ruo-Can Qian,a   Da-Wei Lia  and  Yi-Tao Long*a  

* Corresponding authors

a Key Laboratory for Advanced Materials & Department of Chemistry, East China University of Science and Technology, 130 Meilong Road, Shanghai, P. R. China
E-mail: ytlong@ecust.edu.cn

Abstract

Herein, a pH-sensitive probe has been designed based on DNA modified gold nanoparticles (AuNPs) for Raman/fluorescence dual-imaging of the intracellular pH distribution. In the acidic environment of cancer cells, the configuration change of DNA on the probe surface could turn “on” Raman/fluorescence signals simultaneously.

Graphical abstract: Raman/fluorescence dual-sensing and imaging of intracellular pH distribution

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Article information

DOI
https://doi.org/10.1039/C5CC07697H
Article type
Communication
Submitted
14 Sep 2015
Accepted
08 Oct 2015
First published
08 Oct 2015

Chem. Commun., 2015,51, 17584-17587

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Raman/fluorescence dual-sensing and imaging of intracellular pH distribution

Y. Cao, R. Qian, D. Li and Y. Long, Chem. Commun., 2015, 51, 17584 DOI: 10.1039/C5CC07697H

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