Issue 66, 2015

Peptide-based hydrogen sulphide-releasing gels

Abstract

An aromatic peptide amphiphile was designed for delivery of the signaling gas H2S. The peptide self-assembled in water into nanofibers that gelled upon charge screening. The non-toxic gel slowly released H2S over 15 hours, and the presence of H2S in endothelial cells was verified using a fluorescent H2S probe.

Graphical abstract: Peptide-based hydrogen sulphide-releasing gels

Supplementary files

Article information

Article type
Communication
Submitted
15 Jun 2015
Accepted
11 Jul 2015
First published
20 Jul 2015
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2015,51, 13131-13134

Author version available

Peptide-based hydrogen sulphide-releasing gels

J. M. Carter, Y. Qian, J. C. Foster and J. B. Matson, Chem. Commun., 2015, 51, 13131 DOI: 10.1039/C5CC04883D

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