Issue 57, 2015

The detection of multiple DNA targets with a single probe using a conformation-sensitive acoustic sensor

Abstract

By using an acoustic wave methodology that allows direct sensing of biomolecular conformations, we achieved the detection of multiple target DNAs using a single probe, exploiting the fact that each bound target results in a hybridized product of a different shape.

Graphical abstract: The detection of multiple DNA targets with a single probe using a conformation-sensitive acoustic sensor

Supplementary files

Article information

Article type
Communication
Submitted
24 Apr 2015
Accepted
05 Jun 2015
First published
05 Jun 2015

Chem. Commun., 2015,51, 11504-11507

Author version available

The detection of multiple DNA targets with a single probe using a conformation-sensitive acoustic sensor

A. Tsortos, A. Grammoustianou, R. Lymbouridou, G. Papadakis and E. Gizeli, Chem. Commun., 2015, 51, 11504 DOI: 10.1039/C5CC03436A

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