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Issue 40, 2015
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Synthesis and anticancer properties of fucoidan-mimetic glycopolymer coated gold nanoparticles

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Abstract

Gold nanoparticles coated with fucoidan-mimetic glycopolymers were synthesized that displayed good colloidal stability and promising anti-cancer properties. Fucoidan mimetic glycopolymers on their own were nontoxic, while glycopolymer coated gold nanoparticles displayed selective cytotoxicity to human colon cancer cell lines (HCT116) while it was non-toxic to mouse fibroblast cells (NIH3T3).

Graphical abstract: Synthesis and anticancer properties of fucoidan-mimetic glycopolymer coated gold nanoparticles

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Publication details

The article was received on 22 Mar 2015, accepted on 10 Apr 2015 and first published on 10 Apr 2015


Article type: Communication
DOI: 10.1039/C5CC02387D
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Citation: Chem. Commun., 2015,51, 8532-8535
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    Synthesis and anticancer properties of fucoidan-mimetic glycopolymer coated gold nanoparticles

    M. Tengdelius, D. Gurav, P. Konradsson, P. Påhlsson, M. Griffith and O. P. Oommen, Chem. Commun., 2015, 51, 8532
    DOI: 10.1039/C5CC02387D

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