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Issue 41, 2015
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Mononuclear nonheme iron(III) complexes that show superoxide dismutase-like activity and antioxidant effects against menadione-mediated oxidative stress

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Abstract

This communication describes the superoxide dismutase (SOD)-like activity of mononuclear iron(III) complexes with pentadentate monocarboxylamido ligands. The SOD activity can be controlled by the electronic nature of the substituent group on the ligand. The nitro-substituted complex showed clear cytoprotective activity against menadione-mediated oxidative stress in cultured cells.

Graphical abstract: Mononuclear nonheme iron(iii) complexes that show superoxide dismutase-like activity and antioxidant effects against menadione-mediated oxidative stress

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Publication details

The article was received on 10 Mar 2015, accepted on 20 Apr 2015 and first published on 20 Apr 2015


Article type: Communication
DOI: 10.1039/C5CC02019K
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2015,51, 8702-8704
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    Mononuclear nonheme iron(III) complexes that show superoxide dismutase-like activity and antioxidant effects against menadione-mediated oxidative stress

    Y. Hitomi, Y. Iwamoto, A. Kashida and M. Kodera, Chem. Commun., 2015, 51, 8702
    DOI: 10.1039/C5CC02019K

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