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Issue 9, 2015
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Compact multi-enzyme pathways in P. pastoris

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Abstract

We report for the first time the functional simultaneous expression of nine genes from a single 2A peptide based polycistronic expression construct. The feasibility and arising opportunities for the biosynthetic pathway balancing for chemical production were demonstrated by the co-expression of the violacein and carotenoid biosynthesis pathways.

Graphical abstract: Compact multi-enzyme pathways in P. pastoris

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Publication details

The article was received on 28 Oct 2014, accepted on 03 Dec 2014 and first published on 03 Dec 2014


Article type: Communication
DOI: 10.1039/C4CC08502G
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Citation: Chem. Commun., 2015,51, 1643-1646
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    Compact multi-enzyme pathways in P. pastoris

    M. Geier, P. Fauland, T. Vogl and A. Glieder, Chem. Commun., 2015, 51, 1643
    DOI: 10.1039/C4CC08502G

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