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Issue 12, 2015
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Aerobic C–N bond activation: a simple strategy to construct pyridines and quinolines

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Abstract

Inspired by the autoxidation processes, a dioxygen induced C–N bond activation of primary alkyl amines was demonstrated toward the synthesis of pyridines and quinolines. The transition-metal free conditions with O2 as the sole oxidant make this transformation very attractive. Notably, the substrate applicability of different kinds of ketones is greatly broadened for this transformation.

Graphical abstract: Aerobic C–N bond activation: a simple strategy to construct pyridines and quinolines

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Publication details

The article was received on 13 Oct 2014, accepted on 17 Dec 2014 and first published on 18 Dec 2014


Article type: Communication
DOI: 10.1039/C4CC08074B
Citation: Chem. Commun., 2015,51, 2286-2289
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    Aerobic C–N bond activation: a simple strategy to construct pyridines and quinolines

    K. Wu, Z. Huang, C. Liu, H. Zhang and A. Lei, Chem. Commun., 2015, 51, 2286
    DOI: 10.1039/C4CC08074B

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