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Issue 1, 2015
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Reversible biomechano-responsive surface based on green fluorescent protein genetically modified with unnatural amino acids

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Abstract

GFP has been genetically modified at two specific positions of its molecular architecture. These modifications allow its covalent attachment onto PEG brushes grafted on functionalized silicone surfaces. The stretching of this material leads to a reversible decrease of the fluorescence intensity due to stretch-induced forces applying on GFP molecules.

Graphical abstract: Reversible biomechano-responsive surface based on green fluorescent protein genetically modified with unnatural amino acids

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Publication details

The article was received on 22 Sep 2014, accepted on 05 Nov 2014 and first published on 06 Nov 2014


Article type: Communication
DOI: 10.1039/C4CC07486F
Author version available: Download Author version (PDF)
Citation: Chem. Commun., 2015,51, 232-235
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    Reversible biomechano-responsive surface based on green fluorescent protein genetically modified with unnatural amino acids

    J. Longo, C. Yao, C. Rios, N. T. T. Chau, F. Boulmedais, J. Hemmerlé, P. Lavalle, S. M. Schiller, P. Schaaf and L. Jierry, Chem. Commun., 2015, 51, 232
    DOI: 10.1039/C4CC07486F

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