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Issue 8, 2015
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Coupling a solid phase microextraction (SPME) probe with ambient MS for rapid enrichment and detection of phosphopeptides in biological samples

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Abstract

In this study, we developed a probe-electrospray ionization method by coupling a SPME probe modified with nanosized TiO2 directly to nanoESI-MS for the phosphoproteome analysis, which demonstrated excellent selectivity and sensitivity for enrichment of phosphopeptides in complex biological samples.

Graphical abstract: Coupling a solid phase microextraction (SPME) probe with ambient MS for rapid enrichment and detection of phosphopeptides in biological samples

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Publication details

The article was received on 22 Nov 2014, accepted on 09 Feb 2015 and first published on 09 Feb 2015


Article type: Communication
DOI: 10.1039/C4AN02156H
Citation: Analyst, 2015,140, 2599-2602
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    Coupling a solid phase microextraction (SPME) probe with ambient MS for rapid enrichment and detection of phosphopeptides in biological samples

    Y. Zhao, X. Gong, X. Si, Z. Wei, C. Yang, S. Zhang and X. Zhang, Analyst, 2015, 140, 2599
    DOI: 10.1039/C4AN02156H

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