Issue 4, 2014

Hybrid nanoparticles with CO2-responsive shells and fluorescence-labelled magnetic cores

Abstract

CO2-responsive polymer poly(N,N-diethylaminoethylmethacrylate)-modified magnetic nanoparticles (Fe3O4@dye/SiO2–PDEAEMA) were synthesized by atom transfer radical polymerization from the surfaces of silica coated, dye-labelled iron oxide nanoparticles (Fe3O4@dye/SiO2). TEM, FT-IR, and TGA confirmed and quantified the grafted polymer brushes. The prepared magnetic nanoparticles (MNPs) were fluorescence labelled, as shown by the fluorescence spectra and fluorescence microscopy images. This indicated that the nanoparticles could be utilized as imaging probes to monitor the movement of biological cells or other systems. The PDEAEMA polymer brushes on the surface of MNPs endowed them with a protein adsorption ability. The polymer was also CO2-responsive, so it was a CO2-triggered reversible protein adsorption/release material, which was demonstrated by the bovine serum albumin (BSA) adsorption experiments. The results indicated that the reversible adsorption/release of protein by bubbling CO2 and N2 alternately was easy to achieve.

Graphical abstract: Hybrid nanoparticles with CO2-responsive shells and fluorescence-labelled magnetic cores

Additions and corrections

Article information

Article type
Paper
Submitted
13 Sep 2013
Accepted
31 Oct 2013
First published
01 Nov 2013

J. Mater. Chem. B, 2014,2, 437-442

Hybrid nanoparticles with CO2-responsive shells and fluorescence-labelled magnetic cores

J. Guo, N. Wang, J. Wu, Q. Ye, C. Zhang, X. Xing and J. Yuan, J. Mater. Chem. B, 2014, 2, 437 DOI: 10.1039/C3TB21264E

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