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Issue 20, 2014
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Protein recognition by a surface imprinted colloidal array

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Abstract

A label-free and easy-to-prepare biosensor for the fast and naked-eye detection of proteins was developed in this study. A closely packed crystalline array was self-assembled in ethanol–water (1 : 1, v/v) from the surface imprinted silica (SIS) colloid for hemoglobin bovine (Hb). The reflection of the molecular imprinted colloidal array (MICA) red shifted by 23 nm in response to 1.0 mg mL−1 of Hb at pH 7.0. Compared with the non-imprinted colloidal array (NICA), MICA has a higher selectivity towards the target protein, and can recognize the target protein via an “induced-fit” mechanism.

Graphical abstract: Protein recognition by a surface imprinted colloidal array

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Publication details

The article was received on 04 Jan 2014, accepted on 24 Feb 2014 and first published on 24 Feb 2014


Article type: Communication
DOI: 10.1039/C4TA00048J
Citation: J. Mater. Chem. A, 2014,2, 7165-7169
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    Protein recognition by a surface imprinted colloidal array

    W. Chen, W. Lei, M. Xue, F. Xue, Z. Meng, W. Zhang, F. Qu and K. J. Shea, J. Mater. Chem. A, 2014, 2, 7165
    DOI: 10.1039/C4TA00048J

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