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A bivalent small molecule-drug conjugate directed against carbonic anhydrase IX can elicit complete tumour regression in mice

N. Krall,a   F. Prettob and   D. Neri*a  
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a
ETH Zurich, Institute of Pharmaceutical Sciences, HCI, G391.4, Vladimir-Prelog-Weg 1-5/10, 8093, Zurich, Switzerland
E-mail: dario.neri@pharma.ethz.ch
b
Philochem AG, Libernstrasse 3, 8112 Otelfingen, Switzerland
Chem. Sci., 2014,5, 3640-3644

DOI: 10.1039/C4SC00685B
Received 05 Mar 2014, Accepted 19 Jun 2014
First published online 20 Jun 2014
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