Jump to main content
Jump to site search

Issue 7, 2014
Previous Article Next Article

Rh(III)-catalyzed C–H functionalization/aromatization cascade with 1,3-dienes: a redox-neutral and regioselective access to isoquinolines

Author affiliations

Abstract

An efficient rhodium(III)-catalyzed redox-neutral C–H activation/cyclization/isomerization strategy to prepare isoquinolines with complete regioselectivity from aromatic oxime esters and diverse 1,3-dienes is described. The advantages of this process are: (1) no need for an external oxidant; (2) simple and convenient reaction conditions; (3) complete regioselectivity; (4) broad scope of substrates.

Graphical abstract: Rh(iii)-catalyzed C–H functionalization/aromatization cascade with 1,3-dienes: a redox-neutral and regioselective access to isoquinolines

Back to tab navigation
Please wait while Download options loads

Supplementary files

Publication details

The article was received on 27 Feb 2014, accepted on 27 Mar 2014 and first published on 28 Mar 2014


Article type: Edge Article
DOI: 10.1039/C4SC00628C
Citation: Chem. Sci., 2014,5, 2869-2873
  •   Request permissions

    Rh(III)-catalyzed C–H functionalization/aromatization cascade with 1,3-dienes: a redox-neutral and regioselective access to isoquinolines

    D. Zhao, F. Lied and F. Glorius, Chem. Sci., 2014, 5, 2869
    DOI: 10.1039/C4SC00628C

Search articles by author