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Issue 6, 2014
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Ambient condition oxidation in individual liposomes observed at the single molecule level

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Abstract

Single particle imaging studies on liposomes stained with lipophilic, fluorogenic, peroxyl radical-trapping probes show oxidation taking place during standard liposome preparation conditions. A ratiometric assay involving the fluorogenic probe enables quantifying oxidative events at the single particle level. The assay provides a general strategy to monitor reactions on individual liposomes.

Graphical abstract: Ambient condition oxidation in individual liposomes observed at the single molecule level

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Publication details

The article was received on 05 Jan 2014, accepted on 07 Apr 2014 and first published on 07 Apr 2014


Article type: Edge Article
DOI: 10.1039/C4SC00033A
Author version available: Download Author version (PDF)
Citation: Chem. Sci., 2014,5, 2525-2529
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    Ambient condition oxidation in individual liposomes observed at the single molecule level

    R. Godin, H. Liu and G. Cosa, Chem. Sci., 2014, 5, 2525
    DOI: 10.1039/C4SC00033A

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