DMAP-promoted multicomponent reaction of cyanoacetylene, MBH carbonate and water: a facile access to functional quaternary carbon†
Abstract
An efficient method for the synthesis of highly functionalized products containing cyanide-substituted quaternary carbon centers via DMAP-promoted multicomponent reactions of cyanoacetylene, Morita–Baylis–Hillman (MBH) carbonate and water was developed. The reactions could be achieved under simple and mild conditions.