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Issue 109, 2014
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One-pot three-component synthesis of pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolines using Fe3O4@SiO2–OSO3H as an efficient heterogeneous nanocatalyst

Ali Maleki*a 
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* Corresponding authors

a Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran
E-mail: maleki@iust.ac.ir
Fax: +98-21-73021584

Abstract

The synthesis of pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolines via a one-pot three-component reaction by using benzene-1,2-dicarbaldehyde, trimethylsilylcyanide and various pyridin-2-amines in the presence of a catalytic amount of superparamagnetic nano-Fe3O4@SiO2 anchored sulfuric acid in ethanol in good-to-high yields is described.

Graphical abstract: One-pot three-component synthesis of pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolines using Fe3O4@SiO2–OSO3H as an efficient heterogeneous nanocatalyst

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Publication details

The article was received on 20 Sep 2014, accepted on 17 Nov 2014 and first published on 24 Nov 2014


Article type: Paper
DOI: 10.1039/C4RA10856F
Citation: RSC Adv., 2014,4, 64169-64173
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    One-pot three-component synthesis of pyrido[2′,1′:2,3]imidazo[4,5-c]isoquinolines using Fe3O4@SiO2–OSO3H as an efficient heterogeneous nanocatalyst

    A. Maleki, RSC Adv., 2014, 4, 64169
    DOI: 10.1039/C4RA10856F

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